Optimized oxidoreductases for medium and large scale industrial biotransformations
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Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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about us
chiraconChiracon GmbH, Luckenwalde, Germany (Chiracon)
Contact information
R. Zuhse, CEO, Chiracon GmbH, Im Biotechnologiepark, Zapfholzweg 1, D-14943 Luckenwalde

Phone: 49 3371 681 299
Fax: 49 3371 681 295
E-mail: zuhse@chiracon.de


Description of the group
Chiracon is an experienced and independent, privately owned company with in-house technology comprising pharmaceutical and analytical laboratories. The company was founded 1998 in Luckenwalde, close to Berlin. The activities of Chiracon are focused on RD, up-scaling and manufacturing of advanced chiral intermediates and active ingredients for the pharmaceutical industry. Serving as a bridge between medicinal chemistry and full-scale manufacturing, Chiracon provides process research services with a core competency in the rapid supply of APIs according to Good Manufacturing Practice (cGMP).

The participation in INDOX will be led by Dr. Ralf Zuhse, CEO of the company. The team has three senior scientists, Dr. Thomas von Schrader (Chemistry, scale-up), Dr. Stephan Quint (Chemistry, development) and Dr. Tahrani (Pharmacy, analytics and quality control).


Main role in INDOX
Chiracon participation in INDOX includes the selection of promising target products and the synthesis of starting materials for the research activities including the analytical validation of the resulting products. In many cases it will be necessary to synthesize the corresponding enantiomers as reference substances and the development of methods for the determination of enantiomeric purity. Further contribution will be the evaluation of peroxygenases and oxidases for the synthesis and the scale up of the technical processes provided by partners.
->Click on the map locations to access information on the partners


Project Coordinator
Prof. Angel T. Martínez
Biological Research Centre (CIB, CSIC)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain.
E-mail: ATMartinez@cib.csic.es
Phone: 34 918373112
Fax: 34 915360432


Angel T. Martínez is Research Professor of CSIC at the group of Biotechnology for Lignocellulosic Biomass of CIB. He is member of ACS, ASM and TAPPI, with around 250 publications mainly related to oxidoreductases and microbial biotechnology.

His experience is supported by participation in more than 55 national and international research projects, in most of them as head researcher. Regarding EC Framework Programmes, he has coordinated projects of Industrial Biotechnology from FP3 to FP7, such as PEROXICATS (KBBE-2010-4-265397), BIORENEW (NMP2-CT-2006-026456), PELAS (QLK3-1999-00590), PITCH (QLK5-1999-01357) and AIR2 (CT93-1219).
Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón