Optimized oxidoreductases for medium and large scale industrial biotransformations
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Project Secretariat
Dr Marta Pérez-Boada
E-mail: MPBoada@cib.csic.es
Consejo Superior de Investigaciones Científicas (CSIC)
Biological Research Centre (CIB)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain
Phone: 34 918373112
Fax: 34 915360432
Mobile: 34 650080476
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about us
UNINAUniversità degli Studi di Napoli Federico II, Naples, Italy (UNINA)

G. Sannia
Contact information
G. Sannia, Department of Chemical Sciences, University of Naples Federico II, cia Cintia, 4, 80126 Napoli, Italy.

Phone: 39 081 674310
Fax: 39 081 674313
E-mail: sannia@unina.it
web-site: www.unina.it


Description of the group
The research group at the University of Naples Federico II has a long standing tradition in industrial applications of basidiomycetous fungi and bacteria, and their degradative enzymatic systems, including oxidases and oxygenases. Recent research interests are: studies of structure-function relationships of monooxygenases and laccases; rational and random mutagenesis of laccases for tailor-adapting enzymes to convert environmental pollutants to non-toxic compounds; applications of free and immobilized oxidative systems to implement bioremediation/biotransformation processes.
The contribution of UNINA will be led by Prof. Giovanni Sannia, who has a long experience in oxidative enzymes and their industrial applications resulting in more than 150 publications. Other members of the group directly participating to the project are:Dr. Alessandra Piscitelli,  expert in oxidative enzymes, their heterologous expression in eukaryotes and prokaryotes, directed evolution, purification and characterization, and application; Dr. Cinzia Pezzella,skilled in immobilization of enzymes on different carriers, protein recombinant expression characterization of oxidative enzymes; Dr. Angela Amoresano, associate researcher, expert in biomolecular mass spectrometry and proteomics; and PhD students working on copper-oxidoreductases (Gemma Macellaro and Lucia Guarino).



Team members
Main role in INDOX
UNINA will lead the laccase studies in INDOX as the responsible for WP3. The main role will be the collaboration to the selection and characterization, improvement, production and immobilization of better performing laccases and their use in the synthesis of dyes and other industrial processes at the lab and pilot scales.
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Project Coordinator
Prof. Angel T. Martínez
Biological Research Centre (CIB, CSIC)
Calle Ramiro de Maeztu 9, E-28040 Madrid, Spain.
E-mail: ATMartinez@cib.csic.es
Phone: 34 918373112
Fax: 34 915360432


Angel T. Martínez is Research Professor of CSIC at the group of Biotechnology for Lignocellulosic Biomass of CIB. He is member of ACS, ASM and TAPPI, with around 250 publications mainly related to oxidoreductases and microbial biotechnology.

His experience is supported by participation in more than 55 national and international research projects, in most of them as head researcher. Regarding EC Framework Programmes, he has coordinated projects of Industrial Biotechnology from FP3 to FP7, such as PEROXICATS (KBBE-2010-4-265397), BIORENEW (NMP2-CT-2006-026456), PELAS (QLK3-1999-00590), PITCH (QLK5-1999-01357) and AIR2 (CT93-1219).
Official webpage of indox [ industrialoxidoreductases ]. Optimized oxidoreductases for medium and large scale industrial biotransformations. This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under Grant Agreement nº: FP7-KBBE-2013-7-613549. © indox 2013. Developed by garcíarincón